Dr. Roger Seheult of http://www.medcram.com illustrates the key differences between the various types of penicillin antibiotic medications:
0:57 – Discovery and brief history of penicillin
1:44 – Penicillinase
2:00 – Semi-synthetic penicillins (methicillin, oxacillin, nafcillin)
3:21 – Need for gram negative antibiotic coverage (E-coli, pseudomonas, etc.)
4:26 – Aminopenicillins (ampicillin, amoxicillin)
4:49 – Extended spectrum penicillin (piperacillin, ticarcillin)
5:14 – Beta-lactamase
5:42 – Beta-lactamase inhibitors (ampicillin/sulbactam and amoxicillin/clavulanic acid
6:35 – Piperacillin/tazobactam
6:54 – Ticarcillin and clavulanate
8:18 – Staph aureus and mutations against penicillin (PCN)
8:42 – MRSA – methicillin-resistant staphylococcus aureus
9:14 – Clindamycin, trimethoprim and sulfamethoxazole, quinolones, vancomycin, daptomycin, and linezolid
10:13 – A note about cross-reactivity / low platelets
10:33 – MSSA and nafcillin
Speaker: Roger Seheult, MD
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
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Produced by Kyle Allred PA-C
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Penicillin | Microorganisms | Biology | FuseSchool
Penicillin is a type of antibiotic that can be used to treat bacterial infections. Really important – antibiotics can only be used to treat bacterial infections.
Penicillin was first discovered in 1928 by a scientist called Alexander Fleming. He noticed that bacteria he was trying to grow would not grow near a certain type of mould fungus. After lots of experimentation he discovered that the mould produced a substance that killed the bacteria. He called this substance penicillin and was able to purify it and use it to treat bacterial infections in people. The drug has gone on to save millions of lives.
CREDITS
Animation & Design: Chloe Fyvie Adams
Narration: Dale Bennett
Script: Bethan Parry
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